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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
Embryonic, DPC unknown

14 matching records from 14 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
Hand2  heart and neural crest derivatives expressed 2   (Synonyms: bHLHa26, dHAND, Ehand2, Hed, Thing2)
Results  Reference
1J:71845 Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, Seidman JG, A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell. 2001 Sep 21;106(6):709-21
1J:109528 Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L, Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development. 2006 Jun;133(11):2263-73
1J:61522 Fernandez-Teran M, Piedra ME, Kathiriya IS, Srivastava D, Rodriguez-Rey JC, Ros MA, Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the sonic hedgehog pathway. Development. 2000 May;127(10):2133-42
1J:46384 Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN, Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet. 1998 Mar;18(3):266-70
1J:175761 Gyurjan I, Sonderegger B, Naef F, Duboule D, Analysis of the dynamics of limb transcriptomes during mouse development. BMC Dev Biol. 2011;11:47
1J:165721 Krawchuk D, Weiner SJ, Chen YT, Lu BC, Costantini F, Behringer RR, Laufer E, Twist1 activity thresholds define multiple functions in limb development. Dev Biol. 2010 Nov 1;347(1):133-46
1J:111148 Marguerie A, Bajolle F, Zaffran S, Brown NA, Dickson C, Buckingham ME, Kelly RG, Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice. Cardiovasc Res. 2006 Jul 1;71(1):50-60
1J:40145 Molkentin JD, Lin Q, Duncan SA, Olson EN, Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 1997 APR 15;11(8):1061-1072
1J:122604 Morikawa Y, D'Autreaux F, Gershon MD, Cserjesi P, Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system. Dev Biol. 2007 Jul 1;307(1):114-26
1J:128015 Sheth R, Bastida MF, Ros M, Hoxd and Gli3 interactions modulate digit number in the amniote limb. Dev Biol. 2007 Oct 15;310(2):430-41
1J:181632 Sun Y, Teng I, Huo R, Rosenfeld MG, Olson LE, Li X, Li X, Asymmetric requirement of surface epithelial beta-catenin during the upper and lower jaw development. Dev Dyn. 2012 Apr;241(4):663-74
1J:207496 Symmons O, Uslu VV, Tsujimura T, Ruf S, Nassari S, Schwarzer W, Ettwiller L, Spitz F, Functional and topological characteristics of mammalian regulatory domains. Genome Res. 2014 Mar;24(3):390-400
1J:163514 Vieux-Rochas M, Mantero S, Heude E, Barbieri O, Astigiano S, Couly G, Kurihara H, Levi G, Merlo GR, Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw. Genesis. 2010 Jun;48(6):262-373
1J:91567 Zakany J, Kmita M, Duboule D, A dual role for Hox genes in limb anterior-posterior asymmetry. Science. 2004 Jun 11;304(5677):1669-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory